ELISA Substrates and Reagents
Medchemexpress LLC Discoidin domain-containing receptor 2, rat | >95.0% | 5 UG
DDR2 is a recombinant rat-derived discoidin domain receptor 2 protein expressed in HEK293 cells with a C-terminal His tag. It is a receptor tyrosine kinase involved in tissue remodeling and extracellular matrix signaling, supplied for research applications such as biochemical assays, signaling studies, and antibody validation.
- Expressed in HEK293 cells.
- Derived from rat sequence.
- C-terminal His tag for detection and purification.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Available in small research quantities suitable for assay development.
- Suitable for biochemical assays, signaling studies, and antibody validation.
Cayman Chemical ChemerIn-9humnacetate 500ug
A peptide agonist of CMKLR1 and CMKLR2; binds to CMKLR1 and CMKLR2 (IC50s = 1.9 and 2.3 nM, respectively); induces calcium mobilization in HEK293T cells expressing either CMKLR1 or CMKLR2 and the G protein Gα15 at 1 µM
American Research Products Inc Human HSPA1A ELISA Kit
This Human Heat Shock 70kDa Protein 1A (HSPA1A) ELISA Kit is a precoated Sandwich ELISA assay designed to detect and quantify the target analyte in serum plasma tissue homogenates cell lysates cell culture supernatants and other biological fluids This product is for Research Use Only
Cayman Chemical InterleukIn-1ahumn ELISA 1ea
A pyrimidine nucleoside and derivative of cytidine found in mammalian mitochondrial rRNA where it stabilizes the structure of 12S rRNA and is essential for mitochondrial translation of oxidative phosphorylation-related proteins maintains normal base pairing with guanine in RNA oligomers
Cell Signaling Technology Hyaluronan Complete Tissue Staining Kit Alexa FluorR 488 1 Kit
Hyaluronan Complete Tissue Staining Kit Alexa FluorR 488 1 Kit
ABclonal Technology Phospho-MEK1-T292 Rabbit pAb
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Cayman Chemical 11keto TStosTRon ELISA n
A DGAT1 inhibitor (IC50 57 nM) selective for DGAT1 over DGAT2 ACAT-1 and ACAT-2 (IC50s >10000 nM for all) inhibits HCV replication in HCV-infected Huh7.5 cells at 50 UM. inhibits palmitic acid-induced apoptosis and increases in triglyceride levels in MIN6 cells decreases serum triglyceride levels in an oral lipid tolerance test in dogs at 1 mg/kg
Sino Biological Recombinant Rabbit BAFF/BLyS/TNFSF13B Protein (hFc Tag), MALS-verified 100
A DNA sequence encoding the Rabbit BAFF/BLyS/TNFSF13B (B8RHI7) (Glu145-Leu290) was expressed with the Fc region of human IgG1 at the N-terminus.
ABclonal Technology Phospho-eIF2α-S51 Rabbit pAb
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2, MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).
ABclonal Technology Phospho-Raptor-Ser792 Rabbit pAb
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology Phospho-HSP27/HSPB1-S82 Rabbit pAb
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Cayman Chemical THUNDERPhospho-p38a MAPK 96Wel
Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-p38αβγ MAPK14/11/12 (T180/Y182) in cell lysates
ABclonal Technology Phospho-NMDAR1-S896/S897 Rabbit pAb
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
Cayman Chemical ProgSTRon ELISA ntIsRum 100dtn
A cell-penetrating peptide inhibitor of EPS8 nuclear translocation induces apoptosis and cell cycle arrest in the G0/G1 phase in THP-1 HL-60 and U937 cells at 70 UM reduces phosphorylated ERK STAT3 and Akt levels in THP-1 HL-60 and U937 cells at 35 or 70 UM reduces tumor volume without affecting body weight in a U937 mouse xenograft model at 55 mg/kg every other day decreases tumor volume alone or in combination with daunorubicin in a KG-1 AML mouse xenograft model at 50 mg/kg every other day